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PhD candidate to develop OCT on an integrated photonics chip

Apply before: 29 May 2019
Type of Employment: Fixed Term Contract
Working hours: 36 hours per week
Discipline: AMC Medical Research (AMR)

What you are going to do

Optical Coherence Tomography (OCT) is a medical imaging modality for 3D visualization of tissue at micrometer scale resolutions. Next to imaging, optical properties of the tissue can be derived which are related to the tissue’s physiological function (such as perfusion) and structural organization (which can be an indicator of e.g. cancer progression). The potential for OCT as a diagnostic aide has been recognized in various medical fields, ranging from opthalmology and cardiology to dermatology, urology and gastroentrology. However, application is currently constrained by physical factors such as instrument size and imaging geometry. The goal of this project is to remove these constraints by replacing the conventional bulk optics OCT system with a highly miniaturized instrument based on integrated photonics technologies. In recent years, our research group in collaboration with other partners have demonstrated that it is feasible to manufacture the various components (waveguides, splitters, arrayed waveguide gratings) in integrated photonic technology. In this project, we, together with TU Eindhoven and 6 companies, will realize and demonstrate a miniaturized imaging system that uses 1300nm and 1550nm wavelength ranges to enable diagnostic quantitative imaging of biological tissue. To achieve this two types of photonic integrated circuits will be combined. New semiconductor photonic integration technology operating at 1300nm and new innovative tunable laser systems will be developed and investigated. With these combined wavelength ranges, you will explore the possibilities to obtain functional information of living tissues.

What we expect from you

You have a recent Msc in physics or (biomedical)b engineering (or equivalent). You have affinity for applying optical technology to medical applications. Skills from the optics or electronics lab are considered a pre. Programming skills, specifically for controlling instrumentation, data (image) acquisition and processing are required, preferably in LabVIEW or Matlab. You are motivated to become an independent researcher. You are a team player that can communicate and work efficiently with the various project partners.

Where you are going to work

The Biomedical photonics group within the Biomedical Engineering & Physics department of Amsterdam UMC, location AMC (BMEP), headed by prof. Van Leeuwen, investigates the interaction of light with tissue in order to obtain quantitative functional information. Thereto, various medical devices and dedicated signal analysis have been developed for and evaluated in the clinic, e.g. cardiology and urology. For OCT specifically, the correlation of OCT signal with intrinsic physical and optical properties of (living) tissue has been studied for over 15 years. This group is leading on designing and building OCT setups for clinical applications, the physical interpretation of data obtained using OCT (such as measurements on blood flow) as well as of clinical application of OCT using miniaturized devices. Currently the biomedical photonics group contains 5 staff members, 4 postdocs and 25 PhD students.

What we offer you

We offer you ample opportunity for development, deepening and broadening, additional training and a place to grow! Working at AMR means working in an inspiring and professional environment where development is encouraged in every respect.

  • The maximum gross monthly salary based on a 36-hour work week is € 3.020 (scale OIO CAO UMC).
  • The base salary does not include holiday pay (8%) and a year-end bonus (8.3%).
  • We offer a contract for 4 years.
  • In addition to excellent accessibility by public transport, AMC also has a sufficient number of parking spaces for employees.
  • Pension is accrued at Be Frank.

For an overview of all our other terms of employment, see www.werkenbijamc.nl/arbeidsvoorwaarden-amr

Let’s meet

If you would like to apply directly, please use the ‘apply’ button on this page.
If you would like more information, please feel free to contact Ton van Leeuwen (Department head), via t.g.vanleeuwen@amc.nl.

We look forward to meeting you!