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PhD Position on Pediatric Image-guided (Adaptive) Radiotherapy

Apply before: 31 August 2019
Type of Employment: Fixed Term Contract
Working hours: 36 hours per week
Discipline: AMC Medical Research (AMR)

What you are going to do

Cancer treatment of children has been successful during the last decades with dramatically improved survival rates. Radiotherapy is one of the cornerstones of this success. However, radiotherapy for children comes with risks of adverse effects that the patients develop during their life time. In this position you will work on improvement of radiotherapy for children. By analyzing 3D and 4D images (CT, Cone Beam CT and MRI), acquired during radiotherapy, we study how irradiation can be delivered more precisely to spare healthy tissues as much as possible. Organ motion (caused by e.g. breathing or bowel motion) typically necessitates to irradiate a large volume to ensure irradiation of the tumor. Irradiation of such a large volume causes damage to healthy organs that surround the tumor. A part of this project focuses on analysis of organ motion. This can lead to better adaptation of the radiation beam to the tumor location and thus yield sparing of healthy organs. Moreover, proton therapy, recently being introduced in the Netherlands, provides excellent physical characteristics to even better target the tumor with a sharply peaked dose deposition. However, image guidance is even more important for proton therapy than for conventional photon therapy. A geometrical miss of the tumor yields a high risk of damage to healthy organs. This work involves in a European collaboration network whereby a number of centers contribute imaging data and expertise. The research is embedded in the clinical physics group.

What we expect from you

We are looking for an enthusiastic, motivated and creative PhD candidate with a relevant master’s degree in physics (medical/applied), technical medicine, applied mathematics, or similar. You have knowledge of (medical) imaging, and experience with (building) data bases is a pre. You feel a strong affinity with working in an internationally oriented multi-disciplinary academic hospital environment, where you will have the opportunity to create and pursue you own research ideas. International data collection requires organizational and communication skills, and willingness to travel. Furthermore, you are skilled to statistically analyze and interpret comprehensive data sets, and to write an present the research results in scientific English.

Where you are going to work

You are going to work at one of the largest radiation oncology departments in Europe: the Department of Radiation Oncology, Amsterdam UMC, location AMC. The department has 15 linear accelerators, all equipped with state-of-the art image guidance facilities including MR-guidance. Proton therapy, being a standard indication for pediatric radiotherapy, will be introduced within the next few years. The physics research group of which you will be part, has the ambition to be leading in (pre)clinical research. Clinical physicists, radiation oncologists and researchers (including PhD candidates) collaborate closely in a multi-disciplinary setting. Research lines focus on adaptive image-guided radiotherapy, deformable image registration, and advanced optimization of brachytherapy and hyperthermia.

What we offer you

We offer you ample opportunity for development, deepening and broadening, additional training and a place to grow! Working at AMR means working in an inspiring and professional environment where development is encouraged in every respect.

  • Your salary will be € 2.422,- gross per month in the first year and up to € 3.103,- gross per month in the fourth year, according to the PhD candidate salary scale .
  • The base salary does not include holiday pay (8%) and a year-end bonus (8.3%).
  • We offer a contract for 4 years.
  • In addition to excellent accessibility by public transport, AMC also has a sufficient number of parking spaces for employees.
  • Pension is accrued at Be Frank.

For an overview of all our other terms of employment, see www.werkenbijamc.nl/arbeidsvoorwaarden-amr.

Let’s meet

If you would like to apply directly, please use the ‘apply’ button on this page.
If you would like more information, please feel free to contact Arjan Bel (Head clinical physics radiotherapy) via 020-5666895 or a.bel@amsterdamumc.nl, or Irma van Dijk (Postdoctoral researcher) via 020-5666823 or i.w.vandijk@amsterdamumc.nl.

We look forward to meeting you!