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PhD student for HIV-1 Cure program

Apply before: 20 November 2019
Type of Employment: Fixed Term Contract
Working hours: 36 hours per week
Discipline: AMC Medical Research (AMR)
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What you are going to do

We are looking for highly motivated PhD students who are interested in innovative research to cure HIV-1. You need to be able to work in a multidisciplinary team and have affinity/experience with molecular virology and/or immunology.

You will participate in a multidisciplinary research collaboration that aims to identify the molecular signature of the HIV-1 reservoir in order to develop innovative biologicals to eliminate the reservoir.

You will use innovative immunological methods to identify latent infected HIV-1 cells and determine the signature by single cell sequencing. You will develop specific engineered antibodies to target and eradicate the HIV-1 infected cells. Moreover, genetic CRISPR-CAS approaches can also be used to remove HIV-1 integrated genome from cells. You will investigate the efficacy of the method in vitro and using both in vivo humanized mice and ex vivo patient models.

The Target2Cure research is a collaboration between different research groups within the Amsterdam UMC (location AMC) and UMC Utrecht. There are two PhD student positions within the Amsterdam UMC and one postdoctoral position in UMC Utrecht.

What we expect from you

We are looking for PhD student candidates with a Masters in Biomedical sciences or equivalent studies and experience in virology and/or immunology is preferred.

You should have the ability to work independently as well as in a collaborative team.

Where you are going to work

This exciting HIV-1 Cure program is a new research collaboration between researchers from the Department of Experimental Immunology (Dr. Ribeiro, Dr. Kootstra, Prof. Geijtenbeek,) and Experimental Virology (Prof. Sanders, Dr. Van Gils, Dr. Pasternak, Prof Berkhout) at the Amsterdam UMC, and  Medical Microbiology (Dr. Nijhuis) at the UMC Utrecht.

PhD students will work individually on different aspects of the research program but collaborate within work packages together with postdocs.

What we offer you

We offer you ample opportunity for development, deepening and broadening, additional training and a place to grow! Working at AMR means working in an inspiring and professional environment where development is encouraged in every respect.

• The maximum gross monthly salary based on a 36-hour work week is € 3.103,- (scale 21 CAO UMC).
• The base salary does not include holiday pay (8%) and a year-end bonus (8.3%).
• We offer a contract for 12 months.
• In addition to excellent accessibility by public transport, AMC also has a sufficient number of parking spaces for employees.
• Pension is accrued at Be Frank.

For an overview of all our other terms of employment, see https://werkenbijamc.nl/arbeidsvoorwaarden-amr/

Let’s meet

If you would like to apply directly, please use the ‘apply’ button on this page.
If you would like more information, please feel free to contact Teunis Geijtenbeek (Professor), via t.b.geijtenbeek@amsterdamumc.nl or Neeltje Kootstra (Associate Professor), via n.a.kootstra@amsterdamumc.nl.

We look forward to meeting you!

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