The LONGITOOLS project is a European project focusing on the lifelong impact of the environment on cardio-metabolic health. Environmental factors, including air and noise pollution and the built environment, are typically associated with cardiovascular and metabolic non-communicable diseases (NCDs), e.g. obesity, type 2 diabetes, heart diseases and atherosclerosis. The extent to which these exposures may cause their attributed health effects directly or indirectly as a result of associations to an individual’s psychosocial context is largely unknown. NCDs arise from a lifelong process influencing anthropometric, glycaemic, cardiac and lipid-related health trajectories. Risks may start as early as during the fetal period and are modified during sensitive periods in childhood, adolescence and adulthood. Despite this, research has not focused enough on the life-course characterization of the exposome and the application of this to health and disease. The LONGITOOLS project will investigate longitudinal trajectories of exposure and cardio-metabolic health combining data from birth cohorts, registers and biobanks. The AMC will lead a subpart of the project focusing on environmental determinants of longitudinal health trajectories of cardio-metabolic health from pregnancy to older age. To this end, data from the AMC-based Dutch famine birth cohort will be used as well as data from other large European cohorts. The postdoc will be responsible for the daily management and execution of the AMC part of the project. He/she will communicate with the other European partners, perform analyses of combined large data sets as well as analyses on data from the Dutch famine birth cohort, draft manuscripts and reports on deliverables for the LONGITOOLS project.
We are looking for a junior postdoc with a PhD in Medicine or related area of expertise. As a candidate, you are interested in and preferably have knowledge on early life origins of disease and cardio-metabolic health. You have experience with large data sets and advanced statistical analysis of complex data (using statistical packages as SPSS and R) and an interest in complexity science. An important part of your job will be to harmonise and link relevant variables from different cohorts to generate environmental variables contributing to four health trajectories, i.e. anthropometry, cardiovascular, glycaemic, and lipid-related from pregnancy to old age. The harmonised variables will be used to examine the pathways through which adverse environmental exposures during critical windows may influence the four health trajectories. Causal diagrams will be applied to prespecify potential confounding, mediating and modifying factors for each analysis. In addition to being able to do this, you have a high level of English proficiency, you are a good manager and a team player. Finally, you have good time management skills enabling you to meet the projects’ deadlines for finishing analyses, reports and other deliverables.
The postdoc will be part of the research team of dr. Susanne de Rooij and prof. Tessa Roseboom. The team studies early life origins of health and part of the team focuses on the fetal programming of diseases in older age, such as cognitive decline and dementia using the Dutch famine birth cohort. The team is part of the Department of Clinical Epidemiology, Biostatistics and Bio informatics at location AMC of the Amsterdam UMC.
We offer you ample opportunity for development, deepening and broadening, additional training and a place to grow! Working at AMR means working in an inspiring and professional environment where development is encouraged in every respect.
• The maximum gross monthly salary based on a 36-hour work week is € 4.481,- (scale 10 CAO UMC).
• The base salary does not include holiday pay (8%) and a year-end bonus (8.3%).
• We offer a contract for 12 months with the possiblity to extend up to two years.
• In addition to excellent accessibility by public transport, AMC also has a sufficient number of parking spaces for employees.
• Pension is accrued at Be Frank.
For an overview of all our other terms of employment, see https://werkenbijamc.nl/arbeidsvoorwaarden-amr/
If you would like to apply directly, please use the ‘apply’ button on this page.
If you would like more information, please feel free to contact Susanne de Rooij (UHD), via 020 – 56 64660 or firstname.lastname@example.org.
Live job interviews are currently scheduled for June, but actual dates will be dependent on the Corona crisis measures.
We look forward to meeting you!
Because of the coronavirus, healthcare is our main focus now in Amsterdam UMC. This means that it will probably take longer before we give you feedback on your application, or schedule job interviews. Thank you for your understanding!